Clinical Indication ID & Name
Any patient receiving solid organ transplantation (only in cases where passenger lymphocyte syndrome is suspected)
Test Group
Solid Tumours (Adult)
Specialties
Test code
M242.1
Test name
STR Testing
Target genes
Test scope
Short tandem repeat analysis
Test method/ technology
Complex targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Test code
M242.2
Test name
Sex chromosome FISH
Target genes
X chromosome, Y chromosome
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
Cancer WGS Clinician pack
Education resources
n/a
Service updates
n/a
Request form download
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form