Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

Childhood solid tumours

Clinical Indication ID & Name

R359

Childhood solid tumours

Test Group

Inherited cancer

Specialties

Oncology Clinical Genetics

Test code

R359.1

Test name

N/A

Target genes

Tumour predisposition - childhood onset (243)

Test scope

n/a

Test method/ technology

WES or Medium panel

Optimal Family Structure

n/a

Eligibility Criteria

Any presentation of an invasive solid tumour diagnosed at age ≤ 18 , where no other Testing Criteria are met, OR other test did not identify pathogenic variant, AND the patient has NOT been investigated through:
1. Tumour WGS, OR
2. Another large germline cancer susceptibility panel, OR
3. Exome test through GMS or an alternative route

Genetic testing may occasionally be appropriate outside these criteria following discussion at a specialist MDT with a cancer geneticist present

Test code

R359.2

Test name

N/A

Target genes

Tumour predisposition - childhood onset (243)

Test scope

n/a

Test method/ technology

Exon level CNV detection by MLPA or equivalent

Optimal Family Structure

n/a

Eligibility Criteria

Any presentation of an invasive solid tumour diagnosed at age ≤ 18 , where no other Testing Criteria are met, OR other test did not identify pathogenic variant, AND the patient has NOT been investigated through:
1. Tumour WGS, OR
2. Another large germline cancer susceptibility panel, OR
3. Exome test through GMS or an alternative route

Genetic testing may occasionally be appropriate outside these criteria following discussion at a specialist MDT with a cancer geneticist present

Commissioning group

Specialised

Overlapping idications

• The associated paediatric cancer clinical indication (M coded) should be used for somatic testing

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

gos-tr.norththamesgenomics@nhs.net

Supporting documents

Rare Disese WGS Clinician pack

Education resources

n/a

Service updates

n/a

Request form download

RD Non-WGS - Record of Discussion

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form