Clinical Indication ID & Name
Follicular Lymphoma
Test Group
Haematology
Specialties
Test code
M103.1
Test name
t(14:18)(q32:q21) IGH-BCL2 FISH/RT-PCR
Target genes
IGH-BCL2
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M103.2
Test name
BCL2 rearrangement FISH
Target genes
BCL2
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M103.3
Test name
BCL6 rearrangement FISH
Target genes
BCL6
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M103.4
Test name
Multi-target NGS panel - small variant (CARD11, CREBBP, EZH2, ARID1A, EP300, MEF2B, FOXO1)
Target genes
CARD11, CREBBP, EZH2, ARID1A, EP300, MEF2B, FOXO1
Test scope
Small variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M103.5
Test name
Multi-target NGS panel - structural variant (IGH-BCL2, BCL2, BCL6)
Target genes
IGH-BCL2, BCL2, BCL6
Test scope
Structural variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
Cancer WGS Clinician pack
Education resources
n/a
Service updates
n/a
Request form download
n/a
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form