Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

High Grade Lymphoma

Clinical Indication ID & Name

M99

High Grade Lymphoma

Test Group

Haematology

Specialties

Test code

M99.1

Test name

MYC rearrangement FISH

Target genes

MYC

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.2

Test name

t(8:14)(q34:q32) IGH-MYC FISH/RT-PCR

Target genes

IGH-MYC

Test scope

Structural variant detection

Test method/ technology

FISH/Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.3

Test name

t(8:22)(q24:q11) IGK-MYC FISH/RT-PCR

Target genes

IGK-MYC

Test scope

Structural variant detection

Test method/ technology

FISH/Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.4

Test name

t(2:8)(p12:q24) IGL-MYC FISH/RT-PCR

Target genes

IGL-MYC

Test scope

Structural variant detection

Test method/ technology

FISH/Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.5

Test name

BCL2 rearrangement FISH

Target genes

BCL2

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.6

Test name

t(14:18)(q32:q21) IGH-BCL2 FISH/RT-PCR

Target genes

IGH-BCL2

Test scope

Structural variant detection

Test method/ technology

FISH/Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.7

Test name

BCL6 rearrangement FISH

Target genes

BCL6

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M99.8

Test name

WGS Germline and Tumour

Target genes

All including burden / signature

Test scope

All variant types

Test method/ technology

WGS

Optimal Family Structure

n/a

Eligibility Criteria

For paediatric patients only

Test code

M99.9

Test name

Mutli-target NGS panel - structural variant (IGH-MYC, IGK-MYC, IGL-MYC, IGH-BCL2, other rearrangements of MYC, BCL2, BCL6)

Target genes

IGH-MYC, IGK-MYC, IGL-MYC, IGH-BCL2, MYC,BCL2, BCL6

Test scope

Structural variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

rmh-tr.moleculardiagnostics@nhs.net

Supporting documents

Cancer WGS Clinician pack

Education resources

n/a

Service updates

n/a

Request form download

n/a

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form