Clinical Indication ID & Name
Membranoproliferative glomerulonephritis (83)
Test Group
Renal
Specialties
Test code
R197.1
Test name
N/A
Target genes
Membranoproliferative glomerulonephritis (83)
Test scope
n/a
Test method/ technology
Small panel
Optimal Family Structure
n/a
Eligibility Criteria
Idiopathic membranoproliferative glomerulonephritis (MPGN) or C3 glomerulopathy with onset before the age of 18, together with one of:
1. Family history of MPGN or unexplained end-stage renal disease, OR
2. Renal transplant is being considered, OR
3. Patient is being considered for complement inhibitory therapies
Test code
R197.2
Test name
N/A
Target genes
CFH;CFHR
Test scope
n/a
Test method/ technology
MLPA or equivalent
Optimal Family Structure
n/a
Eligibility Criteria
Idiopathic membranoproliferative glomerulonephritis (MPGN) or C3 glomerulopathy with onset before the age of 18, together with one of:
1. Family history of MPGN or unexplained end-stage renal disease, OR
2. Renal transplant is being considered, OR
3. Patient is being considered for complement inhibitory therapies
Commissioning group
Highly Specialised
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
Rare Disese WGS Clinician pack
Education resources
n/a
Service updates
n/a
Request form download
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form